Follow us

Latest Advancements in 

Antibody Engineering

1.Introduction:

Antibodies, also known as immunoglobulins, are Y-shaped proteins produced by the immune system in response to the presence of foreign substances called antigens.These proteins play a crucial role in the immune response by recognizing and binding to specific antigens, marking them for destruction by other immune cells. 

Antibodies are highly specific, with each type able to recognize a particular antigen. This specificity makes them invaluable tools in research, diagnostics, and therapy.

 2. Latest Advancements:

Recent advancements in antibody engineering have revolutionized the field of immunotherapy. 

One of the most notable breakthroughs is the development of bispecific antibodies (bsAbs), which can simultaneously bind to two different epitopes or antigens. This technology has opened up new possibilities for targeted cancer therapy, as bsAbs can redirect immune cells to specifically target and kill tumor cells.

Various bispecific antibodies (bsAbs)

 Another significant advancement is the creation of antibody-drug conjugates (ADCs), where antibodies are linked to cytotoxic drugs. ADCs allow for targeted delivery of potent drugs to cancer cells while sparing healthy tissues, minimizing side effects.